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Where Should You Buy Your Supplements? The Truth About Quality, Safety, and Who You Can Trust

woman in store holding shopping basket with medicines and supplement bottles
Apothecary and Co - June 3, 2025

In today’s world, supplements are available just about everywhere—big box stores, online marketplaces, and even social media. But just because they’re easy to find doesn’t mean they’re all safe, effective, or even worth your money.

The supplement industry is largely unregulated, which means there’s a huge range in quality—and that can directly impact your health.

Not All Supplements Are Created Equal

bowls of assorted supplements in various colors, shapes, and sizes

Most over-the-counter vitamins sold in retail stores or online are mass-produced with cheap fillers, artificial colors, and synthetic forms of nutrients that your body can’t easily absorb. For example, many low-quality supplements use cyanocobalamin (a synthetic form of B12) instead of the more bioavailable methylcobalamin, or folic acid instead of methylfolate.

Your body has to work extra hard—sometimes unsuccessfully—to convert these forms into something usable. And for many people with genetic mutations like MTHFR, that conversion may not happen at all.

On top of that, the Recommended Daily Allowance (RDA) values listed on most vitamin labels are outdated—some dating back to the 1950s. These values were designed to prevent diseases like scurvy or rickets, not to support modern health in the face of chronic stress, nutrient-depleted soil, and processed diets. The vitamin C in a typical once-daily multivitamin may have been enough to prevent scurvy back then—but it’s hardly enough to support immune resilience today.

What Are Professional-Grade Supplements?

Professional-grade supplements are in a different league. These are therapeutic-grade formulas sold only through licensed healthcare practitioners. They’re made with high-quality, bioavailable ingredients in clinical dosages that are designed to actually do something—not just check a box.

Brands like Apothecary & Co, Metagenics, and Designs for Health have strict manufacturing standards, often backed by research and third-party testing. You’ll notice they include effective forms of nutrients (like methylated B vitamins) in dosages that make a real difference.

They’re not cheap knockoffs. And they’re not sold on Amazon.

Yes, Amazon Supplements Can Be Dangerous

woman looking at supplement bottle label and researching ingredients on laptop

We know it's tempting to grab supplements from Amazon or TikTok because it's quick and convenient. But here’s the truth: there are real, documented risks to doing so.

  • A 2022 study published in JAMA Network Open analyzed 30 immune-supporting supplements purchased from Amazon. 17 of them had inaccurate labels, 13 were misbranded, and 9 contained ingredients not listed on the label.
    View the study

  • NOW Foods, a highly respected supplement manufacturer, performed independent testing on CoQ10 products purchased on Amazon. They found that 5 out of 10 products contained less than 20% of the labeled potency.
    NOW Foods report summary

  • The FDA has flagged supplements sold on Amazon that were found to contain dangerous hidden pharmaceutical ingredients like sibutramine (a banned weight-loss drug) and phenolphthalein (linked to cancer risk).
    Read more on SELF

  • In late 2024, a supplement sold on Amazon labeled as hyaluronic acid was recalled after the FDA found it was contaminated with diclofenac (a prescription NSAID) and omeprazole.
    NY Post coverage

  • Well-known brands like Pure Encapsulations have had to deal with counterfeit versions of their products circulating on Amazon, raising serious concerns about safety, storage conditions, and ingredient authenticity.
    ConsumerLab report

What to Look for Instead

To make sure you’re getting high-quality, effective supplements:

  • Buy directly from the manufacturer or through a licensed practitioner (like Apothecary & Co).

  • Look for third-party testing seals like the USP Verified Mark—this shows that the product meets purity, strength, and safety standards.

  • Avoid buying supplements from TikTok, Facebook, or third-party Amazon sellers. You don’t know where the product came from, how it was stored, or if it’s even the real thing.

  • Ask your healthcare provider which brands they trust and why. Don’t just go with whatever’s trending online.

Bottom Line: Trust Where You Buy

At the end of the day, your health is too important to gamble with knockoff supplements. You wouldn’t buy prescription medications from a random TikTok shop—why would your supplements be any different?

When you shop at Apothecary & Co, you’re not just getting a bottle of pills—you’re getting a promise of clinical integrity, practitioner-backed formulations and personalized recommendations you can trust.

So no, you don’t need to buy your supplements from the same place you buy your toilet paper.
Choose smart. Choose safe. Choose therapeutic-grade supplements that actually work.

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